Article
Analysis of heat shock protein polymorphisms in a large family with autoimmune thyroid diseases.
Archives de l'Institut Pasteur de Tunis - 1 Jan 2000
Bougacha-Elleuch N, Tamouza R, Bellassouad M, Jouida J, Abid M, Maalej A, Makni H, Ayadi H
Abstract excerpt
Graves disease and Hashimoto's thyroiditis are autoimmune thyroid diseases (AITD) in which the genetic contribution is complex. The purpose of this work was to analyze the influence of hsp70 gene polymorphisms on the susceptibility to AITD. The hsp 70-2 and hsp 70-hom polymorphism was analyzed, by PCR-RFLP using PstI and NcoI enzymes, respectively, in 40 patients affected with AITD and 38 related healthy...
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