Article
A thyroid hormone receptor beta gene polymorphism associated with Graves' disease.
Journal of molecular endocrinology - 1 Dec 1995
Tassi V, Scarnecchia L, Di Cerbo A, Pirro M T, Di Paola R, Liuzzi A, Torlontano M, Zingrillo M, D'Aloiso L, De Filippis V
Abstract excerpt
Autoimmune thyroid diseases (AITDs) are clustered in families, but the nature of this clustering is still poorly understood. One possible approach to the identification of genetic factors interacting with the AITDs is the study of the association between polymorphic markers and AITDs themselves....
Topics
- Adult
- Alleles
- Autoimmune Diseases
- Base Sequence
- Deoxyribonuclease HindIII
- Gene Frequency
- Genotype
- Graves Disease
- Humans
- Italy
- Middle Aged
- Molecular Sequence Data
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Receptors, Thyroid Hormone