Article
Heat shock protein 70 (HSP70) and complement C4 genotypes in patients with hyperthyroid Graves' disease.
Clinical and experimental immunology - 1 Apr 1991
Ratanachaiyavong S, Demaine A G, Campbell R D, McGregor A M
Abstract excerpt
The genetic polymorphisms of the heat shock protein 70 (HSP70) and complement component C4 were investigated in 90 patients with hyperthyroid Graves' disease and 92 normal control subjects. The 8.5-kb PstI HSP70 allele was strongly associated with Graves' disease when compared with controls (P less than 0.001). The presence of the 8.5-kb PstI HSP70 allele was strongly associated with a deletion of the C4A gene in...
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