Article
Meiosis-specific failure of cell cycle progression in fission yeast by mutation of a conserved beta-tubulin residue.
Molecular biology of the cell - 1 Mar 2004
Paluh Janet L, Killilea Alison N, Detrich H William, Downing Kenneth H
Abstract excerpt
The microtubule cytoskeleton is involved in regulation of cell morphology, differentiation, and cell cycle progression. Precisely controlled dynamic properties are required for these microtubule functions. To better understand how tubulin's dynamics are embedded in its primary sequence, we investigated in vivo the consequences of altering a single, highly conserved residue in beta-tubulin that lies at the...
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