Article
Nuclear actin-related protein is required for chromosome segregation in Toxoplasma gondii.
Molecular and biochemical parasitology - 1 Jan 2012
Suvorova Elena S, Lehmann Margaret M, Kratzer Stella, White Michael W
Abstract excerpt
Apicomplexa parasites use complex cell cycles to replicate that are not well understood mechanistically. We have established a robust forward genetic strategy to identify the essential components of parasite cell division. Here we describe a novel temperature sensitive Toxoplasma strain, mutant 13-20C2, which growth arrests due to a defect in mitosis. The primary phenotype is the mis-segregation of duplicated...
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