Article
Bulky DNA adducts and breast cancer risk in the prospective EPIC-Italy study.
Breast cancer research and treatment - 1 Sept 2011
Saieva Calogero, Peluso Marco, Masala Giovanna, Munnia Armelle, Ceroti Marco, Piro Sara, Sera Francesco, Bendinelli Benedetta, Pala Valeria, Sieri Sabina, Tumino Rosario, Giurdanella Maria Concetta, Panico Salvatore, Mattiello Amalia, Vineis Paolo, Polidoro Silvia, Matullo Giuseppe, Palli Domenico
Abstract excerpt
The role of environmental carcinogen exposure in breast cancer development has long been suspected, but no specific association has been identified so far. A few molecular epidemiology studies reported that DNA adducts detected by different methods are associated with a modest increase of breast cancer risk. We aimed to evaluate the association between bulky DNA adducts, detected by the (32)P-postlabelling method...
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