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Article

CMV-hFasL transgenic mice are sensitive to low doses of streptozotocin-induced type I diabetes mellitus.

Acta pharmacologica Sinica - 1 Dec 2003

Lin Bo, Zhang Zhen-Lin, Yu Lu-Yang, Guo Li-He

Abstract excerpt

AIM: To investigate the role of Fas-FasL pathway in the pathogenesis of streptozotocin (STZ)-induced type I diabetes mellitus. METHODS: Low dose injections of STZ were used to induce type I diabetes mellitus in the CMV-hFasL transgenic mice. Blood glucose concentration was measured with Glucotrand Plus blood glucose test strips. Expression of hFasL was detected by RT-PCR and Western blotting. The severity of...

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PMID: 14653944

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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