Article
Blood glucose level and survival in streptozotocin-treated human chymase transgenic mice.
The Chinese journal of physiology - 28 Feb 2011
Rafiq Kazi, Sherajee Shamshad J, Fan Yu-Yan, Fujisawa Yoshihide, Takahashi Yoshimasa, Matsuura Junji, Hase Naoki, Urata Hidenori, Nakano Daisuke, Hitomi Hirofumi, Nishiyama Akira
Abstract excerpt
A growing body of evidence suggests the potential role of chymase in organ injury in diabetes. We investigated blood glucose levels and survival in transgenic mice carrying the human chymase gene (Tg). Intraperitoneal injections of streptozotocin (STZ) (200, 100, 75 and 50 mg/kg in total, i.p.) w...
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