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Article

Dietary exposure to chlorpyrifos affects systemic and hepatic immune-cell phenotypes in diabetic mice.

Toxicology - 30 Mar 2021

Chen Yi-Ching, Pai Man-Hui, Chen Yi-Tien, Hou Yu-Chen

Abstract excerpt

Hyperglycemia induces low-grade systemic inflammation and immune dysregulation, leading to overstated reactions to immune stimuli and diabetes-related organ damage. Tissue inflammation is characterized by leukocyte infiltration, and T cells play crucial roles in directing leukocyte-mediated inflammatory responses. The aim of the study was to investigate the effects of dietary exposure to chlorpyrifos (CPF) on...

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PMID: 33524429
DOI: 10.1016/j.tox.2021.152698

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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