Article
Fibrinogen B beta polymorphisms do not directly contribute to an altered in vitro clot structure in humans.
Thrombosis and haemostasis - 1 Dec 2003
Maghzal Ghassan J, Brennan Stephen O, George Peter M
Abstract excerpt
Fibrinogen B beta polymorphisms, such as the -455 G/A and the Arg448Lys amino acid substitution, have been shown to increase the risk of atherothrombotic disease. Although these polymorphisms are related to fibrinogen concentrations, their effect on fibrin clot structure has not been extensively studied. We examined the frequency of the fibrinogen B beta -455 G/A polymorphism in a group of myocardial infarction...
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