Article
The thyroid hormone receptor beta gene: structure and functions in the brain and sensory systems.
Thyroid : official journal of the American Thyroid Association - 1 Nov 2003
Jones Iwan, Srinivas Maya, Ng Lily, Forrest Douglas
Abstract excerpt
Thyroid hormone profoundly influences the development of the vertebrate nervous system. The thyroid hormone receptor beta gene (Thrb) is a key mediator of many of these actions. The Thrb gene is complex, spanning up to 400 kb in mammals, and differentially expresses distinct receptor subtypes through independent tissue-specific promoters and alternative splicing. These receptors serve a range of functions in the...
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