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Article

Resistance to Thyroid Hormone Beta: A Focused Review.

Frontiers in endocrinology - 1 Jan 2021

Pappa Theodora, Refetoff Samuel

Abstract excerpt

Resistance to thyroid hormone (RTH) is a clinical syndrome defined by impaired sensitivity to thyroid hormone (TH) and its more common form is caused by mutations in the thyroid hormone receptor beta (THRB) gene, termed RTHβ. The characteristic biochemical profile is that of elevated serum TH levels in absence of thyrotropin suppression. Although most individuals are considered clinically euthyroid, there is...

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Identifiers

PMID: 33868182
DOI: 10.3389/fendo.2021.656551
PMCID: PMC8044682

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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