Thyroid hormones and the central nervous system of mammals (Review)

doi:10.3892/mmr.1.3.279

Article

Thyroid hormones and the central nervous system of mammals (Review)

1 May 2008

Abstract excerpt

The thyroid hormones (THs) L-thyroxine (T4) and L-triiodothyronine (T3) have a profound influence on the development and maturation of the mammalian brain, both before and after birth. Any impairment in the supply of THs to the developing nervous system leads to severe and irreversible changes in both the overall architecture and functions of the brain and causes, in humans, neurological and motor deficits known...

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