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Article

The human THRB thyroid hormone receptor gene and the puzzle of retinal disease phenotypes.

Developmental biology - 1 Jul 2026

Forrest Douglas, Ng Lily, Cho Young-Wook, Liu Ye, Liu Hong

Abstract excerpt

The THRB thyroid hormone receptor gene has attracted growing attention for its role in retinal development and disease. This gene has particularly critical roles in cone photoreceptors, the specialized cells that mediate color vision and high acuity vision. THRB controls the diversity of cone types that are required for color vision and influences cone survival in mammalian model species and human retinal...

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Identifiers

PMID: 41997342
DOI: 10.1016/j.ydbio.2026.04.004
PMCID: PMC13487493

Genes

THRB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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