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Article

C-C chemokine receptor 2 gene polymorphism in Japanese patients with multiple sclerosis.

Journal of neuroimmunology - 1 Dec 2003

Miyagishi Ryuji, Niino Masaaki, Fukazawa Toshiyuki, Yabe Ichiro, Kikuchi Seiji, Tashiro Kunio

Abstract excerpt

C-C chemokine receptor 2 (CCR2) is a receptor for chemoattractant protein-1 (MCP-1) and associated with infiltrating lymphocytes in chronic active multiple sclerosis (MS) lesions. To study the role of CCR2 gene in the development of MS, we investigated the CCR2-64I polymorphism in 122 MS patients and 112 healthy controls in a Japanese population. We also analysed the influence of CCR2-64I polymorphism on the...

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Source

Identifiers

PMID: 14644039
DOI: 10.1016/j.jneuroim.2003.09.003

Genes

CCR2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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