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Article

CC chemokine receptor gene polymorphisms in Czech patients with pulmonary sarcoidosis.

American journal of respiratory and critical care medicine - 1 Sept 2000

Petrek M, Drábek J, Kolek V, Zlámal J, Welsh K I, Bunce M, Weigl E, Du Bois R

Abstract excerpt

Genes for the chemokine receptors CCR5 and CCR2 are characterized by polymorphisms resulting in a nonfunctional receptor expression. Ligands for CCR2 and CCR5 (chemokines monocyte chemotactic protein-1 [MCP-1] and RANTES) are implicated in the pathogenesis of sarcoidosis. We have, therefore, analyzed polymorphisms of CCR5 (32-bp deletion in CCR5 gene [Delta32]) and of CCR2 (replacement of valine by isoleucine in...

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Source

Identifiers

PMID: 10988120
DOI: 10.1164/ajrccm.162.3.2001022

Genes

CCR2
CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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