Article
Interleukin 2 receptor α chain gene polymorphisms and risks of multiple sclerosis and neuromyelitis optica in southern Japanese.
Journal of the neurological sciences - 15 Feb 2014
Ainiding Gulibahaer, Kawano Yuji, Sato Shinya, Isobe Noriko, Matsushita Takuya, Yoshimura Satoshi, Yonekawa Tomomi, Yamasaki Ryo, Murai Hiroyuki, Kira Jun-ichi
Abstract excerpt
BACKGROUND: Interleukin 2 receptor α subunit (IL2RA) is a genetic risk for multiple sclerosis (MS) in Caucasians. However, the association between MS and IL2RA in Japanese idiopathic demyelinating diseases of the central nervous system has not been examined. OBJECTIVE: To determine whether IL2RA gene polymorphisms confer risks of developing MS or neuromyelitis optica (NMO) in a Japanese population. METHODS: DNA...
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