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Article

Tissue expression of inducible nitric oxide synthase requires IFN-gamma production by infiltrating splenic T cells: more evidence for immunosuppression by nitric oxide.

Journal of neuroimmunology - 1 Dec 2003

van der Veen Roel C, Dietlin Therese A, Hofman Florence M

Abstract excerpt

The cause of increased severity of experimental allergic encephalomyelitis (EAE) in inducible nitric oxide synthase (iNOS)(-/-) or IFN-gamma(-/-) mice remains unclear. Transient chimeras were generated to examine the source of iNOS-inducing IFN-gamma in the central nervous system (CNS). IFNgamma(-/-) donor cells induced severe EAE but no iNOS expression in the CNS of wild-type recipients upon their immunization....

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Identifiers

PMID: 14644034
DOI: 10.1016/j.jneuroim.2003.09.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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