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Article

Novel chemotherapeutic agents for the treatment of glioblastoma multiforme

1 Dec 2003

Abstract excerpt

During the last few decades, the discovery of novel targets for therapeutic intervention led to the development of chemotherapeutic agents that specifically interfere with altered cellular functions of tumour cells. Genetic alterations in glioblastoma affect cell proliferation and cell cycle control, as well as invasive and metastatic growth. Therefore, innovative therapeutic strategies have been based on drugs...

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PMID: 14640936
DOI: 10.1517/13543784.12.12.1899

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