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Cell death-based treatment of glioblastoma

25 Jan 2018

Abstract excerpt

Cancer cells including glioblastoma have typically evolved multiple mechanisms to escape programmed cell death in order to maintain their survival. Defects in cell death mechanisms not only facilitate tumorigenesis but also ensure resistance to current anticancer therapies. This emphasizes that targeting cell death pathways may provide a means to tackle one of the Achilles' heels of cancer. Over the last decades...

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PMID: 29371590
DOI: 10.1038/s41419-017-0021-8

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