Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic and signaling pathway alterations in glioblastoma: relevance to novel targeted therapies.

Frontiers in bioscience : a journal and virtual library - 1 May 2003

Rao Ravi D, Uhm Joon H, Krishnan Sunil, James C David

Abstract excerpt

Glioblastomas multiforme (GBM) is the most common malignant primary brain tumor in adults. GBM patients have a dismal prognosis, with a median survival of less than 1 year. During the past decade, significant advances have been made in our understanding of the molecular pathogenesis of these tumors. Specific genetic defects have been identified that appear to be important for the development, as well as...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antineoplastic Agents
Share to Cancer-related Molecular Pathways

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Central Nervous System Neoplasms

Share to Drug Design

Share to Glioblastoma

Share to Microtubule and mitosis dynamics

Share to Mutation

Share to Signal Transduction

Source

Identifiers

PMID: 12700121
DOI: 10.2741/897

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic and signaling pathway alterations in glioblastoma: relevance to novel targeted therapies.PMID 12700121Read ↗

Molecular Pathogenesis and Emerging Treatment for Glioblastoma.Semantic proximity Read ↗

Signaling pathways and therapeutic approaches in glioblastoma multiforme (Review)Semantic proximity Read ↗

Glioblastoma Multiforme Oncogenomics and Signaling PathwaysSemantic proximity Read ↗

Deregulated Signaling Pathways in Glioblastoma Multiforme: Molecular Mechanisms and Therapeutic TargetsSemantic proximity Read ↗

Genomic, epigenomic and transcriptomic landscape of glioblastoma.Semantic proximity Read ↗

Applications of emerging molecular technologies in glioblastoma multiforme.Semantic proximity Read ↗

Understanding the Genomic Landscape of Glioblastoma: Opportunities for Targeted TherapiesSemantic proximity Read ↗

Molecular, histopathological, and genomic variants of glioblastoma.Semantic proximity Read ↗

Molecular and Genomic Alterations in Glioblastoma Multiforme.Semantic proximity Read ↗

Key genes altered in glioblastoma based on bioinformatics (Review)Semantic proximity Read ↗

Receptor Tyrosine Kinase Signaling and Targeting in Glioblastoma MultiformeSemantic proximity Read ↗

Glioblastoma: An Update in Pathology, Molecular Mechanisms and BiomarkersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.