One size should not fit all: advancing toward personalized glioblastoma therapy.

Abstract excerpt

Over the past few years, understanding the genetic abnormalities associated with glioblastoma, the most common malignant primary tumor of the central nervous system, has increased dramatically. Mutation types and frequencies have been comprehensively assessed, glioblastoma subclasses have been defined based on gene expression and methylation analyses, and novel mutations implicated in gliomagenesis have been...

Topics

• Brain Neoplasms
• Disease-Free Survival
• Gene Expression Regulation, Neoplastic
• Glioblastoma
• Humans
• Mutation
• Precision Medicine