Article
Molecular targets in glioblastoma.
Future oncology (London, England) - 1 Jan 2015
Zorzan Maira, Giordan Enrico, Redaelli Marco, Caretta Antonio, Mucignat-Caretta Carla
Abstract excerpt
Glioblastoma is the most lethal brain tumor. The poor prognosis results from lack of defined tumor margins, critical location of the tumor mass and presence of chemo- and radio-resistant tumor stem cells. The current treatment for glioblastoma consists of neurosurgery, followed by radiotherapy and temozolomide chemotherapy. A better understanding of the role of molecular and genetic heterogeneity in glioblastoma...
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