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Article

FLT3 mutations are associated with other molecular lesions in AML.

Leukemia research - 1 Jan 2004

Carnicer Maria J, Nomdedéu Josep F, Lasa Adriana, Estivill Camino, Brunet Salut, Aventín Anna, Sierra Jorge

Abstract excerpt

The basic molecular defects underlying acute myeloid leukemias (AML) seem to be caused by inactivating mutations in transcription factors which control normal myeloid differentiation (Class II mutations) and genetic lesions in tyrosine kinases resulting in constitutive activation (Class I mutatio...

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Source

Identifiers

PMID: 14630076
DOI: 10.1016/s0145-2126(03)00125-5

Genes

FLT3
MYH11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14630076-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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