Article
Unexpected correlations between gene expression and codon usage bias from microarray data for the whole Escherichia coli K-12 genome.
Nucleic acids research - 1 Dec 2003
dos Reis Mario, Wernisch Lorenz, Savva Renos
Abstract excerpt
Escherichia coli has long been regarded as a model organism in the study of codon usage bias (CUB). However, most studies in this organism regarding this topic have been computational or, when experimental, restricted to small datasets; particularly poor attention has been given to genes with low CUB. In this work, correspondence analysis on codon usage is used to classify E.coli genes into three groups, and the...
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