A Crosstalk on Codon Usage in Genes Associated with Leukemia.

doi:10.1007/s10528-020-10000-3

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Article

A Crosstalk on Codon Usage in Genes Associated with Leukemia.

Biochemical genetics - 1 Feb 2021

Chakraborty Supriyo, Nath Durbba, Paul Sunanda, Choudhury Yashmin, Ahn Yeongseon, Cho Yoon Shin, Uddin Arif

Abstract excerpt

Leukemia is the outcome of aggregation of damaged white blood cells. Several genes were reported to be associated with the pathogenesis of leukemia. These genes were computationally analyzed to decipher their codon usage bias (CUB) and to identify the prime factors influencing the codon usage profile as no work was reported yet. The mean values of synonymous codon usage order (SCUO) parameter indicated low CUB of...

Topics

Codon
Codon Usage
Computational Biology
DNA Mutational Analysis
Genes, Neoplasm
Genetic Predisposition to Disease
Humans
Leukemia
Mutation
Nucleotides
Protein Folding
RNA, Messenger
Selection, Genetic

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Identifiers

PMID: 32989646
DOI: 10.1007/s10528-020-10000-3

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