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Article

Strand-specific mutational bias influences codon usage of weakly expressed genes in Escherichia coli.

Genes to cells : devoted to molecular & cellular mechanisms - 1 Jun 2010

Powdel Bhesh Raj, Borah Munindra, Ray Suvendra K

Abstract excerpt

According to the selection-mutation-drift theory of molecular evolution, mutation predominates in determining codon usage bias (CUB) in weakly expressed genes (WEG) whereas selection predominates in determining CUB in highly expressed genes (HEG). Strand-specific mutational bias causes compositional asymmetry of the nucleotides between leading and lagging strands (LaS) in bacterial chromosomes. Keeping in view...

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PMID: 20545764
DOI: 10.1111/j.1365-2443.2010.01417.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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