Article
Mechanism of Bruton's tyrosine kinase-mediated recruitment and regulation of TFII-I.
The Journal of biological chemistry - 20 Feb 2004
Sacristán Catarina, Tussié-Luna María Isabel, Logan Sheila M, Roy Ananda L
Abstract excerpt
TFII-I is a ubiquitously expressed multifunctional transcription factor with broad biological roles in transcription and signal transduction in a variety of cell types. We and others have shown that TFII-I can interact physically and functionally with Bruton's tyrosine kinase (Btk), a hematopoietic non-receptor protein tyrosine kinase that is critical for B lymphocyte development. Although TFII-I-Btk interactions...
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