Article
Association of over-expressed TFDP1 with progression of hepatocellular carcinomas.
Journal of human genetics - 1 Jan 2003
Yasui Kohichiroh, Okamoto Hiroyuki, Arii Shigeki, Inazawa Johji
Abstract excerpt
DP-1 is a heterodimerization partner for members of the E2F family of transcription factors; E2F/DP-1 regulates the expression of various cellular promoters, particularly gene products that are involved in the cell cycle. Our earlier studies identified the DP-1 gene ( TFDP1) as a probable target within a 13q34 amplicon that is frequently detected in hepatocellular carcinomas (HCC) and esophageal squamous-cell...
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