Article
Gene amplification of the transcription factor DP1 and CTNND1 in human lung cancer.
The Journal of pathology - 1 Sept 2010
Castillo Sandra D, Angulo Barbara, Suarez-Gauthier Ana, Melchor Lorenzo, Medina Pedro P, Sanchez-Verde Lydia, Torres-Lanzas Juan, Pita Guillermo, Benitez Javier, Sanchez-Cespedes Montse
Abstract excerpt
The search for novel oncogenes is important because they could be the target of future specific anticancer therapies. In the present paper we report the identification of novel amplified genes in lung cancer by means of global gene expression analysis. To screen for amplicons, we aligned the gene expression data according to the position of transcripts in the human genome and searched for clusters of...
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