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Article

Disruption of a regulatory loop between DUSP1 and p53 contributes to hepatocellular carcinoma development and progression.

Journal of hepatology - 1 Jun 2015

Hao Pei-Pei, Li Hua, Lee Mi-Jin, Wang Yun-Peng, Kim Jong-Hyun, Yu Goung-Ran, Lee Sang-Yeop, Leem Sun-Hee, Jang Kyu-Yun, Kim Dae-Ghon

Abstract excerpt

BACKGROUND & AIMS: Altered expression of dual specificity phosphatase 1 (DUSP1) is common in tumors including hepatocellular carcinoma (HCC), and is predictive of tumor progression and poor prognosis. However, the tumor suppressive role of DUSP1 has yet to be clearly elucidated. METHODS: The mole...

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Source

Identifiers

PMID: 25617504
DOI: 10.1016/j.jhep.2014.12.033

Genes

DUSP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25617504-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Disruption of a regulatory loop between DUSP1 and p53 contributes to hepatocellular carcinoma development and progression.PMID 25617504Read ↗

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