Article

The p97-UBXN1 complex regulates aggresome formation

2020-09-03

Abstract excerpt

The recognition and disposal of misfolded proteins are essential for the maintenance of cellular homeostasis. Perturbations in the pathways that promote degradation of aberrant proteins contribute to a variety of protein aggregation disorders broadly termed proteinopathies. It is presently unclear how diverse disease-relevant aggregates are recognized and processed for degradation. The p97 AAA-ATPase in combinatio...

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Literature Corpus work: 94c8a151-2236-505b-b8f9-6927d165fb56
DOI: 10.1101/2020.09.03.281766

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