Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pemphigus foliaceus and desmoglein 1 gene polymorphism: is there any relationship?

Journal of autoimmunity - 1 Sept 2005

Petzl-Erler Maria Luiza, Malheiros Danielle

Abstract excerpt

Transmembrane proteins of the cadherin superfamily, the desmogleins and desmocollins, mediate intercellular adhesion in desmosomes. Autoantibodies to desmoglein 1 (dsg1) are a hallmark of pemphigus foliaceus (PF), a disease characterized by skin blistering resulting from keratinocyte cell detachment. The etiology and pathogenesis of this disease remain poorly understood; however, genetic susceptibility is clearly...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Substitution
Share to Brazil
Share to Desmoglein 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genetic Variation

Share to Linkage Disequilibrium

Share to Pemphigus

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 16242304
DOI: 10.1016/j.jaut.2005.08.001

Genes

DSG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pemphigus foliaceus and desmoglein 1 gene polymorphism: is there any relationship?PMID 16242304Read ↗

Dissecting the associations of endemic pemphigus foliaceus (Fogo Selvagem) with HLA-DRB1 alleles and genotypes.Semantic proximity Read ↗

Epistasis between DSG1 and HLA class II genes in pemphigus foliaceus.Semantic proximity Read ↗

Variation in genes implicated in B-cell development and antibody production affects susceptibility to pemphigus.Semantic proximity Read ↗

HLA class II polymorphism contributes to specify desmoglein derived peptides in pemphigus vulgaris and pemphigus foliaceus.Semantic proximity Read ↗

Individual and epistatic effects of genetic polymorphisms of B-cell co-stimulatory molecules on susceptibility to pemphigus foliaceus.Semantic proximity Read ↗

Polymorphisms within the tumor necrosis factor and lymphotoxin-alpha genes and endemic pemphigus foliaceus--are there any associations?Semantic proximity Read ↗

Cytokine gene polymorphisms in endemic pemphigus foliaceus: a possible role for IL6 variants.Semantic proximity Read ↗

Screening the full leucocyte receptor complex genomic region revealed associations with pemphigus that might be explained by gene regulation.Semantic proximity Read ↗

No evidence for association of the TP53 12139 and the BAX-248 polymorphisms with endemic pemphigus foliaceus (fogo selvagem).Semantic proximity Read ↗

A study of desmoglein 1 autoantibodies in pemphigus vulgaris: racial differences in frequency and the association with a more severe phenotype.Semantic proximity Read ↗

Pemphigus Foliaceus and Pemphigus Vulgaris Autoantibodies React with the Extracellular Domain of Desmoglein-1Semantic proximity Read ↗

Polymorphism of the promoter region and exon 1 of the CTLA4 gene in endemic pemphigus foliaceus (fogo selvagem).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.