Article
The Drosophila selenoprotein BthD is required for survival and has a role in salivary gland development.
Molecular and cellular biology - 1 Dec 2003
Kwon So Yeon, Badenhorst Paul, Martin-Romero F Javier, Carlson Bradley A, Paterson Bruce M, Gladyshev Vadim N, Lee Byeong Jae, Hatfield Dolph L
Abstract excerpt
Selenium is implicated in many diseases, including cancer, but its function at the molecular level is poorly understood. BthD is one of three selenoproteins recently identified in Drosophila. To elucidate the function of BthD and the role of selenoproteins in cellular metabolism and health, we analyzed the developmental expression profile of this protein and used inducible RNA interference (RNAi) to ablate...
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