Article
Mutations in deoB and deoC alter an extracellular signaling pathway required for activation of the gab operon in Escherichia coli.
FEMS microbiology letters - 7 Nov 2003
Joloba Moses L, Rather Philip N
Abstract excerpt
In Escherichia coli, a lacZ fusion to the gabT gene is activated by the accumulation of two self-produced extracellular signals, indole and a second unidentified signal (signal-2). Extracellular indole contributes approximately 25% of this activation and signal-2 is responsible for the majority of activation. Using an E. coli strain unable to produce indole and containing a gabT::lacZ fusion, a genetic approach...
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