Article
Interaction of Bacillus subtilis GabR with the gabTD promoter: role of repeated sequences and effect of GABA in transcriptional activation.
The FEBS journal - 1 Nov 2020
Nardella Caterina, Barile Anna, di Salvo Martino L, Milano Teresa, Pascarella Stefano, Tramonti Angela, Contestabile Roberto
Abstract excerpt
Bacillus subtilis is able to use γ-aminobutyric acid (GABA) found in the soil as carbon and nitrogen source, through the action of GABA aminotransferase (GabT) and succinic semialdehyde dehydrogenase (GabD). GABA acts as molecular effector in the transcriptional activation of the gabTD operon by GabR. GabR is the most studied member of the MocR family of prokaryotic pyridoxal 5'-phosphate (PLP)-dependent...
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