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Article

Phenolyzer: phenotype-based prioritization of candidate genes for human diseases.

Nature methods - 1 Sept 2015

Yang Hui, Robinson Peter N, Wang Kai

Abstract excerpt

Prior biological knowledge and phenotype information may help to identify disease genes from human whole-genome and whole-exome sequencing studies. We developed Phenolyzer (http://phenolyzer.usc.edu), a tool that uses prior information to implicate genes involved in diseases. Phenolyzer exhibits superior performance over competing methods for prioritizing Mendelian and complex disease genes, based on disease or...

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Identifiers

PMID: 26192085
DOI: 10.1038/nmeth.3484
PMCID: PMC4718403

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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