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Article

Direct analysis of tubulin expression in cancer cell lines by electrospray ionization mass spectrometry.

Biochemistry - 21 Oct 2003

Verdier-Pinard Pascal, Wang Fang, Burd Berta, Angeletti Ruth Hogue, Horwitz Susan Band, Orr George A

Abstract excerpt

Differential expression of tubulin isotypes, mutations, and/or post-translational modifications in sensitive and Taxol-resistant cell lines suggests the existence of tubulin-based mechanisms of resistance. Since tubulin isotypes are defined by their C-terminal sequence, we previously described a matrix-assisted laser desorption/ionization time-of-flight mass spectrometry-based analysis of tubulin diversity in...

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Source

Identifiers

PMID: 14556633
DOI: 10.1021/bi0350147

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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