Polymorphic analysis of the human MHC-linked heat shock protein 70 (HSP70-2) and HSP70-Hom genes in insulin-dependent diabetes mellitus (IDDM).

doi:10.1111/j.1365-3083.1993.tb02593.x

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Article

Polymorphic analysis of the human MHC-linked heat shock protein 70 (HSP70-2) and HSP70-Hom genes in insulin-dependent diabetes mellitus (IDDM).

Scandinavian journal of immunology - 1 Nov 1993

Pociot F, Rønningen K S, Nerup J

Abstract excerpt

In the present study we characterized the frequencies of two polymorphisms within the MHC-linked heat shock protein (HSP) 70 genes in patients with insulin-dependent diabetes mellitus (IDDM) (n = 114) and healthy control individuals (n = 110). Significant differences in genotype and allelic frequencies were observed for both polymorphisms between randomly selected patients and controls. However, for the HSP70-2...

Topics

Adult
Alleles
Base Sequence
Diabetes Mellitus, Type 1
Female
Gene Expression
Gene Frequency
Genotype
Heat-Shock Proteins
Histocompatibility Testing
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Major Histocompatibility Complex

Male

Molecular Sequence Data

Polymorphism, Genetic

Polymorphism, Restriction Fragment Length

RNA, Messenger

Random Allocation

Source

Open in PubMed

Identifiers

PMID: 7901896
DOI: 10.1111/j.1365-3083.1993.tb02593.x

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7901896-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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