Heat shock protein 70-hom gene polymorphism and protein expression in multiple sclerosis.

doi:10.1016/j.jneuroim.2016.07.011

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Article

Heat shock protein 70-hom gene polymorphism and protein expression in multiple sclerosis.

Journal of neuroimmunology - 15 Sept 2016

Boiocchi C, Monti M C, Osera C, Mallucci G, Pistono C, Ferraro O E, Nosari G, Romani A, Cuccia M, Govoni S, Pascale A, Montomoli C, Bergamaschi R

Abstract excerpt

Immune-mediated and neurodegenerative mechanisms are involved in multiple sclerosis (MS). Growing evidences highlight the role of HSP70 genes in the susceptibility of some neurological diseases. In this explorative study we analyzed a polymorphism (i.e. HSP70-hom rs2227956) of the gene HSPA1L, which encodes for the protein hsp70-hom. We sequenced the polymorphism by polymerase chain reaction (PCR), in 191 MS...

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PMID: 27609295
DOI: 10.1016/j.jneuroim.2016.07.011

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