Article
Association analysis of heat shock protein 70 gene polymorphisms in schizophrenia.
European archives of psychiatry and clinical neuroscience - 1 Jun 2008
Kim Jung Jin, Mandelli Laura, Lim Suzy, Lim Hyun Kook, Kwon Oh Joo, Pae Chi Un, Serretti Alessandro, Nimgaonkar Vishwajit L, Paik In-Ho, Jun Tae-Youn
Abstract excerpt
OBJECTIVES: Heat shock proteins (HSPs) are a promising candidate gene in schizophrenia as they are believed to play a protective role in the central nervous system. An alteration in the titers of antibodies to the HSPs in schizophrenia patients has been suggested. Association between the three polymorphisms of HSP70-1 (HSPA1A), HSP70-hom (HSPA1L) and HSP70-2 (HSPA1B) and schizophrenia has been reported....
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