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Article

Gene expression analysis of the corticotrophin-releasing hormone-proopiomelanocortin system in psoriasis skin biopsies.

Acta dermato-venereologica - 6 Jul 2013

Loite Ulvi, Kingo Külli, Reimann Ene, Reemann Paula, Vasar Eero, Silm Helgi, Kõks Sulev

Abstract excerpt

The corticotrophin-releasing hormone-proopiomelanocortin (CRH-POMC) system in the skin coordinates pigmentation and the immune response. The aim of this study was to evaluate the regulatory role of the neuroendocrine system in the pathogenesis of psoriasis. Using quantitative real-time-PCR, mRNA expression levels of 15 genes related to the CRH-POMC system were measured in punch biopsies from lesional and...

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Source

Identifiers

PMID: 23303587
DOI: 10.2340/00015555-1524

Genes

CRH
POMC
MCHR1
ASIP
TYR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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