Article
Gene expression analysis of the corticotrophin-releasing hormone-proopiomelanocortin system in psoriasis skin biopsies.
Acta dermato-venereologica - 6 Jul 2013
Loite Ulvi, Kingo Külli, Reimann Ene, Reemann Paula, Vasar Eero, Silm Helgi, Kõks Sulev
Abstract excerpt
The corticotrophin-releasing hormone-proopiomelanocortin (CRH-POMC) system in the skin coordinates pigmentation and the immune response. The aim of this study was to evaluate the regulatory role of the neuroendocrine system in the pathogenesis of psoriasis. Using quantitative real-time-PCR, mRNA...
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