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Article

Harnessing neuroendocrine controls of keratin expression: A new therapeutic strategy for skin diseases?

13 May 2014

Abstract excerpt

Human skin produces numerous neurohormones and neuropeptides. Recent evidence has shown that the neuroendocrine regulation of human skin biology also extends to keratins, the major structural components of epithelial cells. For example, thyrotropin-releasing hormone, thyrotropin, opioids, prolactin, and cannabinoid receptor 1-ligands profoundly modulate human keratin gene and protein expression in human epidermis...

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PMID: 24823963
DOI: 10.1002/bies.201400006

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