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Article

Immunofocusing: antigen engineering to promote the induction of HIV-neutralizing antibodies.

Trends in molecular medicine - 1 Nov 2003

Pantophlet Ralph, Burton Dennis R

Abstract excerpt

Understanding how neutralizing antibodies recognize HIV could aid the design of antigens that induce protective antibodies upon immunization. There have been several advances in this area of AIDS vaccine research, including structural elucidation of the core of two gp120 envelope glycoproteins and, more recently, determination of the structures of the broadly HIV-1-neutralizing antibodies b12, 2G12 and 2F5. The...

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Source

Identifiers

PMID: 14604823
DOI: 10.1016/j.molmed.2003.09.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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