Article
Molecular determinants of inactivation in voltage-gated Ca2+ channels.
The Journal of physiology - 15 Oct 2000
Hering S, Berjukow S, Sokolov S, Marksteiner R, Weiss R G, Kraus R, Timin E N
Abstract excerpt
Evolution has created a large family of different classes of voltage-gated Ca2+ channels and a variety of additional splice variants with different inactivation properties. Inactivation controls the amount of Ca2+ entry during an action potential and is, therefore, believed to play an important role in tissue-specific Ca2+ signalling. Furthermore, mutations in a neuronal Ca2+ channel (Ca(v)2.1) that are...
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