Article
Origin of Pax and Six gene families in sponges: Single PaxB and Six1/2 orthologs in Chalinula loosanoffi.
Developmental biology - 1 Jul 2010
Hill April, Boll Werner, Ries Carolin, Warner Lisa, Osswalt Marisa, Hill Malcolm, Noll Markus
Abstract excerpt
Pax genes play an important role in networks of transcription factors that determine organogenesis, notably the development of sensory organs. Other members of this regulatory network include transcription factors encoded by the Six gene family. Sponges lack organs and a nervous system, possibly because they have not evolved a Pax/Six network. Here we show that the demosponge Chalinula loosanoffi encodes only one...
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