Article
The genetic control of eye development and its implications for the evolution of the various eye-types.
The International journal of developmental biology - 1 Jan 2002
Gehring Walter J
Abstract excerpt
Mutations in the Pax 6 homologs of mammals and insects prevent eye development and targeted expression of both mammal and insect Pax 6 homologs is capable of inducing functional ectopic eyes. Supported by RNA interference experiments in planarians and nemerteans, these findings indicate that Pax 6 is a universal master control gene for eye morphogenesis. Since all metazoan eyes use rhodopsin as a photoreceptor...
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