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Article

MSH3 protein expression and nodal status in MLH1-deficient colorectal cancers.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jun 2012

Laghi Luigi, Bianchi Paolo, Delconte Gabriele, Celesti Giuseppe, Di Caro Giuseppe, Pedroni Monica, Chiaravalli Anna Maria, Jung Barbara, Capella Carlo, de Leon Maurizio Ponz, Malesci Alberto

Abstract excerpt

PURPOSE: Patients with colorectal cancers (CRC) and high microsatellite instability (MSI) have a better outcome than their chromosome-unstable counterpart. Given the heterogeneity of microsatellite-unstable CRCs, we wanted to see whether any MSI-associated molecular features are specifically associated with prognosis. EXPERIMENTAL DESIGN: One hundred and nine MSI-high CRCs were typed for primary mismatch repair...

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Source

Identifiers

PMID: 22496206
DOI: 10.1158/1078-0432.CCR-12-0175

Genes

MLH1
MSH3
KRAS
MSH6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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