Article
Recent advances in understanding the pathogenesis of polyglutamine diseases: involvement of molecular chaperones and ubiquitin-proteasome pathway.
Journal of chemical neuroanatomy - 1 Oct 2003
Jana Nihar Ranjan, Nukina Nobuyuki
Abstract excerpt
Polyglutamine diseases consist of a group of familial neurodegenerative disorders caused by expression of proteins containing expanded polyglutamine stretch. Over the past several years, tremendous progress has been made in identifying the molecular mechanisms by which the expanded polyglutamine...
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