Article
Essential roles for the Dhr78 orphan nuclear receptor during molting of the Drosophila tracheal system.
Insect biochemistry and molecular biology - 1 Dec 2003
Astle John, Kozlova Tatiana, Thummel Carl S
Abstract excerpt
The Drosophila Dhr78 orphan nuclear receptor has been proposed to play a role in molting of the tracheal cuticle and regulate gene expression during the third larval instar, possibly in response to a novel systemic hormonal signal. Here, we show that there are no essential maternal functions for Dhr78 during development, and that mutants missing both maternal and zygotic Dhr78 function die primarily during second...
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